Preservation Effects and Hippocampal Structural Increases During Healthy AdulthoodPreservation Effects and Hippocampal Structural Increases Dring Healthy Adulthood

INTRODUCTION One major goal of developmental neuroimaging is to identify the functional and structural biomarkers that are predictive of development of cognitive skills, such as executive functioning and general intelligence. Univariate analysis has revealed early insights into the nature of childrens’ intellectual abilities and its relation to neuroanatomical between-subject variations (Shaw et al., 2006). At the same time, multivariate analysis (MVA) has become a promising and highly sensitive technique to study distributed neuronal processing or widespread brain changes in healthy and clinical groups (Bray et al., 2009). Here, we tested the hypothesis of a stable brain structure and cognitive performance covariation using multivariate analysis, independent of the developmental stage in healthy children.